Introduction
Retention in clinical trials is a critical factor that determines the success, validity and costs associated with medical research. High retention rates, as seen in OnTracka’s recent studies boasting >85% retention of all studies from 2024 onwards is evidence of the advantages of using technology in clinical research to ensure that the data collected is comprehensive and reliable while also giving an experience to participants that is not a burden, overly complex or requires multiple platforms. In this article, you will ready about the importance of retention in clinical trials, the challenges researchers face, and the proven strategies improving participant retention in studies completed by companies, like OnTracka.
The Importance of Retention in Clinical Trials
Retention is paramount in maintaining the integrity of clinical trial data. When participants drop out of a study, it can lead to incomplete data sets and exponential increases in expenses, which may compromise the success of the trial.
Regulatory bodies such as the FDA and EMA require comprehensive data from clinical trials to approve new treatments. High retention rates help ensure that the data submitted for approval is robust and meets regulatory standards. Failure to retain participants can lead to regulatory setbacks and increased costs. Retaining participants in clinical trials is also an ethical obligation. Participants who drop out may not receive the full benefits of the intervention being studied, and their health outcomes may be adversely affected. Researchers must prioritise retention to uphold the ethical standards of clinical research.
Challenges in Retaining Participants
One of the primary challenges in retaining participants is the burden placed on them by the study protocol. Frequent visits, complex procedures, and lengthy questionnaires can lead to participant fatigue and dropout. Reducing the burden on participants is crucial for improving retention rates.Participants may lose interest in the study if they do not feel engaged or valued. Poor communication, lack of feedback, and a perceived lack of personal benefit can contribute to dropout rates. Engaging participants through exceptionally designed participant processes and providing clear signals on the study’s progress, as seen in OnTracka, can help mitigate this issue.
Proven Strategies to Improve Retention
Simplifying Study Protocols
Simplifying study protocols can significantly reduce participant burden and improve retention. This can include streamlining procedures through the use of technology to facilitate remote/hybrid models of participation and data collection.
Enhancing Participant Engagement
Engaging participants through the engagement of specialists in this new model of research where the emphasis is placed on designing the participant experience is seen to significantly improve retention, as noted in OnTracka's industry-leading retention rates of >85 on studies that commenced from 2024 onwards.
Providing Support for Adverse Effects
Providing adequate support for participants experiencing adverse effects is crucial. This can include regular check-ins, access to medical care, and clear communication about managing side effects. Ensuring participants feel supported can reduce dropout rates due to adverse effects.
Leveraging Technology
Technology can play a significant role in improving retention. Mobile apps, wearables, and hybrid tools as seen in industry-leading options can reduce the burden on participants by allowing remote data collection and monitoring. These tools can also facilitate regular communication and engagement with participants.
Conclusion
Retention in clinical trials is essential for ensuring data integrity, regulatory compliance, and ethical standards. Researchers face several challenges in retaining participants, including participant burden, lack of engagement, and adverse effects.
However, by simplifying study protocols, enhancing engagement, providing support, offering incentives, and leveraging technology, retention rates can be significantly improved. High retention rates not only benefit the validity of the study but also ensure that participants receive the full benefits of their involvement.
If you are new to offering hybrid/remote clinical trials or you want to speak to the industry-leaders that are leveraging technology to get retention >85%, reach out to the OnTracka team by contacting info@ontracka.com or starting a conversation with us via WhatsApp on +61466119293.
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